BST2/Tetherin Inhibition of Alphavirus Exit

Alphaviruses such as chikungunya virus (CHIKV) and Semliki Forest virus (SFV) are small enveloped RNA viruses that bud from the plasma membrane. Tetherin/BST2 is an interferon-induced host membrane protein that inhibits the release of many enveloped viruses via direct tethering of budded particles t...

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Bibliographic Details
Main Authors: Ooi, Yaw Shin, Dubé, Mathieu, Kielian, Margaret
Format: Online
Language:English
Published: MDPI 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411694/