TM-233, a novel analog of 1′-acetoxychavicol acetate, induces cell death in myeloma cells by inhibiting both JAK/STAT and proteasome activities

TM-233, a novel analog of 1′-acetoxychavicol acetate, induces cell death in myeloma cells by inhibiting both JAK/STAT and proteasome activities

Although the introduction of bortezomib and immunomodulatory drugs has led to improved outcomes in patients with multiple myeloma, the disease remains incurable. In an effort to identify more potent and well-tolerated agents for myeloma, we have previously reported that 1′-acetoxychavicol acetate (A...

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Bibliographic Details
Main Authors: Sagawa, Morihiko, Tabayashi, Takayuki, Kimura, Yuta, Tomikawa, Tatsuki, Nemoto-Anan, Tomoe, Watanabe, Reiko, Tokuhira, Michihide, Ri, Masaki, Hashimoto, Yuichi, Iida, Shinsuke, Kizaki, Masahiro
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409888/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409888/

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