PHA-4/FOXA-regulated microRNA feed forward loops during Caenorhabditis elegans dietary restriction

Dietary restriction (DR) increases life span and delays the onset of age-related diseases across species. However, the molecular mechanisms have remained relatively unexplored in terms of gene regulation. In C. elegans, a popular model for aging studies, the FOXA transcription factor PHA-4 is a robu...

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Bibliographic Details
Main Authors: Pandit, Awadhesh, Jain, Vaibhav, Kumar, Neeraj, Mukhopadhyay, Arnab
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247386/