Comparison of Methods for In-House Screening of HLA-B*57:01 to Prevent Abacavir Hypersensitivity in HIV-1 Care

Comparison of Methods for In-House Screening of HLA-B*57:01 to Prevent Abacavir Hypersensitivity in HIV-1 Care

Abacavir is a nucleoside reverse transcriptase inhibitor used as part of combination antiretroviral therapy in HIV-1-infected patients. Because this drug can cause a hypersensitivity reaction that is correlated with the presence of the HLA-B*57:01 allotype, screening for the presence of HLA-B*57:01...

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Main Authors: De Spiegelaere, Ward, Philippé, Jan, Vervisch, Karen, Verhofstede, Chris, Malatinkova, Eva, Kiselinova, Maja, Trypsteen, Wim, Bonczkowski, Pawel, Vogelaers, Dirk, Callens, Steven, Ruelle, Jean, Kabeya, Kabamba, De Wit, Stephane, Van Acker, Petra, Van Sandt, Vicky, Emonds, Marie-Paule, Coucke, Paul, Sermijn, Erica, Vandekerckhove, Linos
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398410/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398410/

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