The use of HIV-1 integration site analysis information in clinical studies aiming at HIV cure

The mechanisms for the establishment and the persistence of the latent HIV-1 reservoir remain to be completely defined. HIV-1 infection is characterised by the integration of the reverse transcribed proviral DNA into the host's genome. This integrated proviral DNA can remain replication silent,...

Full description

Bibliographic Details
Main Authors: Kiselinova, Maja, De Spiegelaere, Ward, Vandekerckhove, Linos
Format: Online
Language:English
Published: Mediscript Ltd 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967970/