The use of HIV-1 integration site analysis information in clinical studies aiming at HIV cure
The mechanisms for the establishment and the persistence of the latent HIV-1 reservoir remain to be completely defined. HIV-1 infection is characterised by the integration of the reverse transcribed proviral DNA into the host's genome. This integrated proviral DNA can remain replication silent,...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Mediscript Ltd
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967970/ |