Epsin is required for Dishevelled stability and Wnt signaling activation in colon cancer development

Epsin is required for Dishevelled stability and Wnt signaling activation in colon cancer development

Uncontrolled canonical Wnt signaling supports colon epithelial tumor expansion and malignant transformation. Understanding the regulatory mechanisms involved is crucial for elucidating the pathogenesis of and will provide new therapeutic targets for colon cancer. Epsins are ubiquitin-binding adaptor...

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Bibliographic Details
Main Authors: Chang, Baojun, Tessneer, Kandice L., McManus, John, Liu, Xiaolei, Hahn, Scott, Pasula, Satish, Wu, Hao, Song, Hoogeun, Chen, Yiyuan, Cai, Xiaofeng, Dong, Yunzhou, Brophy, Megan L., Rahman, Ruby, Ma, Jian-Xing, Xia, Lijun, Chen, Hong
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397653/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397653/

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