Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled
Extracellular signals are often transduced by dynamic signaling complexes (“signalosomes”) assembled by oligomerizing hub proteins following their recruitment to signal-activated transmembrane receptors. A paradigm is the Wnt signalosome, which is assembled by Dishevelled via reversible head-to-tail...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Cell Press
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065529/ |