Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytes

Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) are the most promising source of cardiomyocytes (CMs) for experimental and clinical applications, but their use is largely limited by a structurally and functionally immature phenotype that most closely resembles embryonic or fetal heart...

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Bibliographic Details
Main Authors: Zhu, Renjun, Blazeski, Adriana, Poon, Ellen, Costa, Kevin D, Tung, Leslie, Boheler, Kenneth R
Format: Online
Language:English
Published: BioMed Central 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396914/