Transcriptome-Guided Functional Analyses Reveal Novel Biological Properties and Regulatory Hierarchy of Human Embryonic Stem Cell-Derived Ventricular Cardiomyocytes Crucial for Maturation

Transcriptome-Guided Functional Analyses Reveal Novel Biological Properties and Regulatory Hierarchy of Human Embryonic Stem Cell-Derived Ventricular Cardiomyocytes Crucial for Maturation

Human (h) embryonic stem cells (ESC) represent an unlimited source of cardiomyocytes (CMs); however, these differentiated cells are immature. Thus far, gene profiling studies have been performed with non-purified or non-chamber specific CMs. Here we took a combinatorial approach of using systems bio...

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Bibliographic Details
Main Authors: Poon, Ellen, Yan, Bin, Zhang, Shaohong, Rushing, Stephanie, Keung, Wendy, Ren, Lihuan, Lieu, Deborah K., Geng, Lin, Kong, Chi-Wing, Wang, Jiaxian, Wong, Hau San, Boheler, Kenneth R., Li, Ronald A.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804624/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804624/

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