The Clinical Relevance of the miR-197/CKS1B/STAT3-mediated PD-L1 Network in Chemoresistant Non-small-cell Lung Cancer

The Clinical Relevance of the miR-197/CKS1B/STAT3-mediated PD-L1 Network in Chemoresistant Non-small-cell Lung Cancer

Programmed cell death ligand-1 (PD-L1) has recently gained considerable attention for its role in tumor immune escape. Here, we identify a miR-197/CKS1B/STAT3-mediated PD-L1 network in chemoresistant non-small-cell lung cancer (NSCLC), independent of immunoinhibitory signals. miR-197 is downregulate...

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Bibliographic Details
Main Authors: Fujita, Yu, Yagishita, Shigehiro, Hagiwara, Keitaro, Yoshioka, Yusuke, Kosaka, Nobuyoshi, Takeshita, Fumitaka, Fujiwara, Tomohiro, Tsuta, Koji, Nokihara, Hiroshi, Tamura, Tomohide, Asamura, Hisao, Kawaishi, Makoto, Kuwano, Kazuyoshi, Ochiya, Takahiro
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395779/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395779/

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