A paradigm shift for extracellular vesicles as small RNA carriers: from cellular waste elimination to therapeutic applications

RNA interference (RNAi) is an important avenue for target-specific gene silencing that is mainly performed by either small interfering RNAs (siRNAs) or microRNAs (miRNAs). This novel method is rapidly becoming a powerful tool for gene therapy. However, the rapid degradation of siRNAs and miRNAs and...

Full description

Bibliographic Details
Main Authors: Hagiwara, Keitaro, Ochiya, Takahiro, Kosaka, Nobuyoshi
Format: Online
Language:English
Published: Springer US 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918124/