Inducible in vivo genome editing with CRISPR/Cas9

Inducible in vivo genome editing with CRISPR/Cas9

CRISPR/Cas9-based genome editing enables the rapid genetic manipulation of any genomic locus without the need for gene targeting by homologous recombination. Here we describe a conditional transgenic approach that allows temporal control of CRISPR/Cas9 activity for inducible genome editing in adult...

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Bibliographic Details
Main Authors: Dow, Lukas E, Fisher, Jonathan, O'Rourke, Kevin P, Muley, Ashlesha, Kastenhuber, Edward R, Livshits, Geulah, Tschaharganeh, Darjus F, Socci, Nicholas D, Lowe, Scott W
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390466/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390466/

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