Lin28b promotes fetal B lymphopoiesis through the transcription factor Arid3a
Zhou et al. demonstrate a requirement for the Let-7–Lin28b axis regulating a shift in development between fetal liver and bone marrow B lymphocyte progenitors in the generation of B1 versus B2 B cells. Specifically, the transcription factor Arid3a, induced by Lin28b and a target of Let-7 miRNA, is s...
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Bibliographic Details
Main Authors: |
Zhou, Yan,
Li, Yue-Sheng,
Bandi, Srinivasa Rao,
Tang, Lingjuan,
Shinton, Susan A.,
Hayakawa, Kyoko,
Hardy, Richard R. |
Format: | Online
|
Language: | English |
Published: |
The Rockefeller University Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387290/
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