Lin28b promotes fetal B lymphopoiesis through the transcription factor Arid3a

Lin28b promotes fetal B lymphopoiesis through the transcription factor Arid3a

Zhou et al. demonstrate a requirement for the Let-7–Lin28b axis regulating a shift in development between fetal liver and bone marrow B lymphocyte progenitors in the generation of B1 versus B2 B cells. Specifically, the transcription factor Arid3a, induced by Lin28b and a target of Let-7 miRNA, is s...

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Bibliographic Details
Main Authors: Zhou, Yan, Li, Yue-Sheng, Bandi, Srinivasa Rao, Tang, Lingjuan, Shinton, Susan A., Hayakawa, Kyoko, Hardy, Richard R.
Format: Online
Language:English
Published: The Rockefeller University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387290/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387290/

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