Prostanoid therapies in the management of pulmonary arterial hypertension
Prostacyclin is an endogenous eicosanoid produced by endothelial cells; through actions on vascular smooth-muscle cells, it promotes vasodilation. Pulmonary arterial hypertension (PAH) is characterized by elevated mean pulmonary artery pressure due to a high pulmonary vascular resistance state. A re...
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Format: | Online |
Language: | English |
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Dove Medical Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386780/ |