Weaning from intravenous prostanoids and normalization of hemodynamics by long-term imatinib therapy in severe idiopathic pulmonary arterial hypertension

Introduction Despite new treatment options targeted at its three main pathogenic pathways, prognosis of idiopathic pulmonary arterial hypertension has remained dismal, with 3-year survival rates around 70 %. Antiproliferative agents have emerged as a new therapeutic concept. However, they may exert...

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Bibliographic Details
Main Authors: Speich, Rudolf, Treder, Ursula, Domenighetti, Guido, Huber, Lars C., Ulrich, Silvia
Format: Online
Language:English
Published: Springer Netherlands 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984669/