Eight challenges in phylodynamic inference

•We outline core challenges in phylodynamic inference.•Evolutionary challenges include selection and recombination.•Epidemiological challenges include population structure and stochasticity.•Methodological challenges include sampling bias and computational complexity.

Bibliographic Details
Main Authors: Frost, Simon D.W., Pybus, Oliver G., Gog, Julia R., Viboud, Cecile, Bonhoeffer, Sebastian, Bedford, Trevor
Format: Online
Language:English
Published: Elsevier 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383806/