Eight challenges in phylodynamic inference
•We outline core challenges in phylodynamic inference.•Evolutionary challenges include selection and recombination.•Epidemiological challenges include population structure and stochasticity.•Methodological challenges include sampling bias and computational complexity.
Main Authors: | Frost, Simon D.W., Pybus, Oliver G., Gog, Julia R., Viboud, Cecile, Bonhoeffer, Sebastian, Bedford, Trevor |
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Format: | Online |
Language: | English |
Published: |
Elsevier
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383806/ |
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