PIK3CA mutations predict recurrence in localized microsatellite stable colon cancer

PIK3CA, which encodes the p110α catalytic subunit of PI3Kα, is one of the most frequently altered oncogenes in colon cancer (CC), but its prognostic value is still a matter of debate. Few reports have addressed the association between PIK3CA mutations and survival and their results are controversial...

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Main Authors: Manceau, Gilles, Marisa, Laetitia, Boige, Valérie, Duval, Alex, Gaub, Marie-Pierre, Milano, Gérard, Selves, Janick, Olschwang, Sylviane, Jooste, Valérie, le Legrain, Michè, Lecorre, Delphine, Guenot, Dominique, Etienne-Grimaldi, Marie-Christine, Kirzin, Sylvain, Martin, Laurent, Lepage, Come, Bouvier, Anne-Marie, Laurent-Puig, Pierre
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380963/