Hi-Corrector: a fast, scalable and memory-efficient package for normalizing large-scale Hi-C data

Summary: Genome-wide proximity ligation assays, e.g. Hi-C and its variant TCC, have recently become important tools to study spatial genome organization. Removing biases from chromatin contact matrices generated by such techniques is a critical preprocessing step of subsequent analyses. The continui...

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Bibliographic Details
Main Authors: Li, Wenyuan, Gong, Ke, Li, Qingjiao, Alber, Frank, Zhou, Xianghong Jasmine
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380031/