Mitochondrial Control by DRP1 in Brain Tumor Initiating Cells

Brain tumor initiating cells (BTICs) coopt the neuronal high affinity GLUT3 glucose transporter to withstand metabolic stress. Here, we investigated another mechanism critical to brain metabolism, mitochondrial morphology. BTICs displayed mitochondrial fragmentation relative to non-BTICs, suggesting...

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Bibliographic Details
Main Authors: Xie, Qi, Wu, Qiulian, Horbinski, Craig M., Flavahan, William A., Yang, Kailin, Zhou, Wenchao, Dombrowski, Stephen M., Huang, Zhi, Fang, Xiaoguang, Shi, Yu, Ferguson, Ashley N., Kashatus, David F., Bao, Shideng, Rich, Jeremy N.
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376639/