Combined Effect of TLR2 Gene Polymorphism and Early Life Stress on the Age at Onset of Bipolar Disorders

Combined Effect of TLR2 Gene Polymorphism and Early Life Stress on the Age at Onset of Bipolar Disorders

Gene-environment interactions may play an important role in modulating the impact of early-life stressful events on the clinical course of bipolar disorder (BD), particularly associated to early age at onset. Immune dysfunction is thought to be an important mechanism linking childhood trauma with ea...

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Bibliographic Details
Main Authors: Oliveira, José, Etain, Bruno, Lajnef, Mohamed, Hamdani, Nora, Bennabi, Meriem, Bengoufa, Djaouida, Sundaresh, Aparna, Chaabane, Arij Ben, Bellivier, Frank, Henry, Chantal, Kahn, Jean-Pierre, Charron, Dominique, Krishnamoorthy, Rajagopal, Leboyer, Marion, Tamouza, Ryad
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366110/

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