Association of HLA-G Low Expressor Genotype with Severe Acute Graft-Versus-Host Disease after Sibling Bone Marrow Transplantation

Background: Human leukocyte antigen-G (HLA-G) molecules play a prominent role in immune tolerance. Structurally similar to their classical HLA homologs, they are distinct by having high rate of polymorphism in the non-coding regions including a functionally relevant 14-base pair (bp) insertion/delet...

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Main Authors: Boukouaci, Wahid, Busson, Marc, Fortier, Catherine, Amokrane, Kahina, de Latour, Régis Peffault, Robin, Marie, Krishnamoorthy, Rajagopal, Toubert, Antoine, Charron, Dominique, Socié, Gérard, Tamouza, Ryad
Format: Online
Language:English
Published: Frontiers Research Foundation 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342264/