Novel Genetic Locus Implicated for HIV-1 Acquisition with Putative Regulatory Links to HIV Replication and Infectivity: A Genome-Wide Association Study

Novel Genetic Locus Implicated for HIV-1 Acquisition with Putative Regulatory Links to HIV Replication and Infectivity: A Genome-Wide Association Study

Fifty percent of variability in HIV-1 susceptibility is attributable to host genetics. Thus identifying genetic associations is essential to understanding pathogenesis of HIV-1 and important for targeting drug development. To date, however, CCR5 remains the only gene conclusively associated with HIV...

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Bibliographic Details
Main Authors: Johnson, Eric O., Hancock, Dana B., Gaddis, Nathan C., Levy, Joshua L., Page, Grier, Novak, Scott P., Glasheen, Cristie, Saccone, Nancy L., Rice, John P., Moreau, Michael P., Doheny, Kimberly F., Romm, Jane M., Brooks, Andrew I., Aouizerat, Bradley E., Bierut, Laura J., Kral, Alex H.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364715/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364715/

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