Validation of Simple Sequence Length Polymorphism Regions of Commonly Used Mouse Strains for Marker Assisted Speed Congenics Screening

Marker assisted speed congenics technique is commonly used to facilitate backcrossing of mouse strains in nearly half the time it normally takes otherwise. Traditionally, the technique is performed by analyzing PCR amplified regions of simple sequence length polymorphism (SSLP) markers between the r...

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Bibliographic Details
Main Authors: Gurumurthy, Channabasavaiah B., Joshi, Poonam S., Kurz, Scott G., Ohtsuka, Masato, Quadros, Rolen M., Harms, Donald W., Lloyd, K. C. Kent
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359823/