Early detection of structural abnormalities and cytoplasmic accumulation of TDP-43 in tissue-engineered skins derived from ALS patients

Early detection of structural abnormalities and cytoplasmic accumulation of TDP-43 in tissue-engineered skins derived from ALS patients

Amyotrophic lateral sclerosis (ALS) is an adult-onset disease characterized by the selective degeneration of motor neurons in the brain and spinal cord progressively leading to paralysis and death. Current diagnosis of ALS is based on clinical assessment of related symptoms. The clinical manifestati...

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Main Authors: Paré, Bastien, Touzel-Deschênes, Lydia, Lamontagne, Rémy, Lamarre, Marie-Soleil, Scott, François-Dominique, Khuong, Hélène T, Dion, Patrick A, Bouchard, Jean-Pierre, Gould, Peter, Rouleau, Guy A, Dupré, Nicolas, Berthod, François, Gros-Louis, François
Format: Online
Language:English
Published: BioMed Central 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359444/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359444/

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