Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy

Frontotemporal lobar degeneration (FTLD) has been subdivided based on the main pathology found in the brains of affected individuals. When the primary pathology is aggregated, hyperphosphorylated tau, the pathological diagnosis is FTLD-tau. When the primary pathology is cytoplasmic and/or nuclear ag...

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Bibliographic Details
Main Authors: Clippinger, Amy K., D’Alton, Simon, Lin, Wen-Lang, Gendron, Tania F., Howard, John, Borchelt, David R., Cannon, Ashley, Carlomagno, Yari, Chakrabarty, Paramita, Cook, Casey, Golde, Todd E., Levites, Yona, Ranum, Laura, Schultheis, Patrick J., Xu, Guilian, Petrucelli, Leonard, Sahara, Naruhiko, Dickson, Dennis W., Giasson, Benoit, Lewis, Jada
Format: Online
Language:English
Published: Springer-Verlag 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690181/