Integrated Microfluidic Card with TaqMan Probes and High-Resolution Melt Analysis To Detect Tuberculosis Drug Resistance Mutations across 10 Genes

Integrated Microfluidic Card with TaqMan Probes and High-Resolution Melt Analysis To Detect Tuberculosis Drug Resistance Mutations across 10 Genes

Genotypic methods for drug susceptibility testing of Mycobacterium tuberculosis are desirable to speed the diagnosis and proper therapy of tuberculosis (TB). However, the numbers of genes and polymorphisms implicated in resistance have proliferated, challenging diagnostic design. We developed a micr...

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Bibliographic Details
Main Authors: Pholwat, Suporn, Liu, Jie, Stroup, Suzanne, Gratz, Jean, Banu, Sayera, Rahman, S. M. Mazidur, Ferdous, Sara Sabrina, Foongladda, Suporn, Boonlert, Duangjai, Ogarkov, Oleg, Zhdanova, Svetlana, Kibiki, Gibson, Heysell, Scott, Houpt, Eric
Format: Online
Language:English
Published: American Society of Microbiology 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357996/

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