Detection of EGFR Mutations by TaqMan Mutation Detection Assays Powered by Competitive Allele-Specific TaqMan PCR Technology

Epidermal growth factor receptor (EGFR) mutations in non-small-cell lung cancer (NSCLC) are predictive of response to treatment with tyrosine kinase inhibitors. Competitive Allele-Specific TaqMan PCR (castPCR) is a highly sensitive and specific technology. EGFR mutations were assessed by TaqMan Muta...

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Bibliographic Details
Main Authors: Roma, Cristin, Esposito, Claudia, Rachiglio, Anna Maria, Pasquale, Raffaella, Iannaccone, Alessia, Chicchinelli, Nicoletta, Franco, Renato, Mancini, Rita, Pisconti, Salvatore, De Luca, Antonella, Botti, Gerardo, Morabito, Alessandro, Normanno, Nicola
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864078/