TEFM is a potent stimulator of mitochondrial transcription elongation in vitro

A single-subunit RNA polymerase, POLRMT, transcribes the mitochondrial genome in human cells. Recently, a factor termed as the mitochondrial transcription elongation factor, TEFM, was shown to stimulate transcription elongation in vivo, but its effect in vitro was relatively modest. In the current w...

Full description

Bibliographic Details
Main Authors: Posse, Viktor, Shahzad, Saba, Falkenberg, Maria, Hällberg, B. Martin, Gustafsson, Claes M.
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357710/