TEFM (c17orf42) is necessary for transcription of human mtDNA

TEFM (c17orf42) is necessary for transcription of human mtDNA

Here we show that c17orf42, hereafter TEFM (transcription elongation factor of mitochondria), makes a critical contribution to mitochondrial transcription. Inactivation of TEFM in cells by RNA interference results in respiratory incompetence owing to decreased levels of H- and L-strand promoter-dist...

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Bibliographic Details
Main Authors: Minczuk, Michal, He, Jiuya, Duch, Anna M., Ettema, Thijs J., Chlebowski, Aleksander, Dzionek, Karol, Nijtmans, Leo G. J., Huynen, Martijn A., Holt, Ian J.
Format: Online
Language:English
Published: Oxford University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105396/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105396/

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