Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination

Crossover recombination facilitates accurate segregation of homologous chromosomes during meiosis1,2. In mammals, poorly characterized regulatory processes ensure every pair of chromosomes obtains at least one crossover, even though the majority of recombination sites yield non-crossovers3. Designat...

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Bibliographic Details
Main Authors: Qiao, Huanyu, Rao, H.B.D. Prasada, Yang, Ye, Fong, Jared H., Cloutier, Jeffrey M., Deacon, Dekker C., Nagel, Kathryn E., Swartz, Rebecca K., Strong, Edward, Holloway, J. Kim, Cohen, Paula E., Schimenti, John, Ward, Jeremy, Hunter, Neil
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356240/