Evidence Implicating CCNB1IP1, a RING Domain-Containing Protein Required for Meiotic Crossing Over in Mice, as an E3 SUMO Ligase
The RING domain-containing protein CCNB1IP1 (Cyclin B1 Interacting Protein 1) is a putative ubiquitin E3 ligase that is essential for chiasmata formation, and hence fertility, in mice. Previous studies in cultured cells indicated that CCNB1IP1 targets Cyclin B for degradation, thus playing a role in...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
MDPI
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139512/ |