Freely orbiting magnetic tweezers to directly monitor changes in the twist of nucleic acids
The double-stranded nature of DNA links its replication, transcription and repair to rotational motion and torsional strain. Magnetic tweezers (MT) are a powerful single-molecule technique to apply both forces and torques to individual DNA or RNA molecules. However, conventional MT do not track rota...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Nature Pub. Group
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354108/ |