Explaining the striking difference in twist-stretch coupling between DNA and RNA: A comparative molecular dynamics analysis
Double stranded helical DNA and RNA are flexible molecules that can undergo global conformational fluctuations. Their bending, twisting and stretching deformabilities are of similar magnitude. However, recent single-molecule experiments revealed a striking qualitative difference indicating an opposi...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666353/ |