Whole exome sequencing reveals recurrent mutations in BRCA2 and FAT genes in acinar cell carcinomas of the pancreas

Whole exome sequencing reveals recurrent mutations in BRCA2 and FAT genes in acinar cell carcinomas of the pancreas

Acinar cell carcinoma of the pancreas is a rare tumor with a poor prognosis. Compared to pancreatic ductal adenocarcinoma, its molecular features are poorly known. We studied a total of 11 acinar cell carcinomas, including 3 by exome and 4 by target sequencing. Exome sequencing revealed 65 nonsynony...

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Bibliographic Details
Main Authors: Furukawa, Toru, Sakamoto, Hitomi, Takeuchi, Shoko, Ameri, Mitra, Kuboki, Yuko, Yamamoto, Toshiyuki, Hatori, Takashi, Yamamoto, Masakazu, Sugiyama, Masanori, Ohike, Nobuyuki, Yamaguchi, Hiroshi, Shimizu, Michio, Shibata, Noriyuki, Shimizu, Kyoko, Shiratori, Keiko
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351513/

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