End-binding 1 protein overexpression correlates with glioblastoma progression and sensitizes to Vinca-alkaloids in vitro and in vivo

End-binding 1 protein overexpression correlates with glioblastoma progression and sensitizes to Vinca-alkaloids in vitro and in vivo

End-binding 1 protein (EB1) is a key player in the regulation of microtubule (MT) dynamics. Here, we investigated the role of EB1 in glioblastoma (GBM) tumor progression and its potential predictive role for response to Vinca-alkaloid chemotherapy. Immunohistological analysis of the 109 human GBM ca...

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Bibliographic Details
Main Authors: Berges, Raphael, Baeza-Kallee, Nathalie, Tabouret, Emeline, Chinot, Olivier, Petit, Marie, Kruczynski, Anna, Figarella-Branger, Dominique, Honore, Stephane, Braguer, Diane
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350359/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350359/

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