Reciprocal Interaction of Wnt and RXR-α Pathways in Hepatocyte Development and Hepatocellular Carcinoma

Reciprocal Interaction of Wnt and RXR-α Pathways in Hepatocyte Development and Hepatocellular Carcinoma

Genomic analysis of human hepatocellular carcinoma (HCC) is potentially confounded by the differentiation state of the hepatic cell-of-origin. Here we integrated genomic analysis of mouse HCC (with defined cell-of-origin) along with normal development. We found a major shift in expression of Wnt and...

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Main Authors: Li, Jinyu, Chanrion, Maia, Sawey, Eric, Wang, Tim, Chow, Edward, Tward, Aaron, Su, Yi, Xue, Wen, Lucito, Robert, Zender, Lars, Lowe, Scott W., Bishop, J. Michael, Powers, Scott
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349704/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349704/

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