CD47 Agonist Peptides Induce Programmed Cell Death in Refractory Chronic Lymphocytic Leukemia B Cells via PLCγ1 Activation: Evidence from Mice and Humans

CD47 Agonist Peptides Induce Programmed Cell Death in Refractory Chronic Lymphocytic Leukemia B Cells via PLCγ1 Activation: Evidence from Mice and Humans

In this study, Santos Susin and colleagues demonstrate that a serum-stable CD47 agonist peptide is highly effective at inducing apoptosis in chronic lymphocytic leukemia B-cells and mice.

Bibliographic Details
Main Authors: Martinez-Torres, Ana-Carolina, Quiney, Claire, Attout, Tarik, Boullet, Heloïse, Herbi, Linda, Vela, Laura, Barbier, Sandrine, Chateau, Danielle, Chapiro, Elise, Nguyen-Khac, Florence, Davi, Frédéric, Le Garff-Tavernier, Magali, Moumné, Roba, Sarfati, Marika, Karoyan, Philippe, Merle-Béral, Hélène, Launay, Pierre, Susin, Santos A.
Format: Online
Language:English
Published: Public Library of Science 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348493/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348493/

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