IL-23 activates innate lymphoid cells to promote neonatal intestinal pathology

IL-23 activates innate lymphoid cells to promote neonatal intestinal pathology

Interleukin-23 (IL-23) responsive group 3 innate lymphoid cells (ILC3s) have been implicated in immune homeostasis and pathogenesis in the adult, but little is known about their roles in the newborn. Here we show that IL-23 promotes conversion of embryonic intestinal Lin−IL-23R+Thy1+ cells into IL-2...

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Bibliographic Details
Main Authors: Chen, Lili, He, Zhengxiang, Slinger, Erik, Bongers, Gerold, Lapenda, Taciana L.S., Pacer, Michelle E., Jiao, Jingjing, Beltrao, Monique F., Soto, Alan J., Harpaz, Noam, Gordon, Ronald E., Ochando, Jordi C., Oukka, Mohamed, Iuga, Alina Cornelia, Chensue, Stephen W., Blander, Julie Magarian, Furtado, Glaucia C., Lira, Sergio A.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326561/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326561/

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