"Flagellated" cancer cells propel anti-tumor immunity

The use of innate immune receptor agonists in cancer therapies has suffered from many drawbacks. Our recent observations suggest that some of these hurdles can be overcome by introducing flagellin into tumor cells to promote tumor antigen presentation by dendritic cells (DCs) and simultaneously tri...

Full description

Bibliographic Details
Main Authors: Garaude, Johan, Blander, J. Magarian
Format: Online
Language:English
Published: Landes Bioscience 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489752/