Pan-Genome Analysis of Human Gastric Pathogen H. pylori: Comparative Genomics and Pathogenomics Approaches to Identify Regions Associated with Pathogenicity and Prediction of Potential Core Therapeutic Targets

Helicobacter pylori is a human gastric pathogen implicated as the major cause of peptic ulcer and second leading cause of gastric cancer (~70%) around the world. Conversely, an increased resistance to antibiotics and hindrances in the development of vaccines against H. pylori are observed. Pan-geno...

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Bibliographic Details
Main Authors: Ali, Amjad, Naz, Anam, Soares, Siomar C, Bakhtiar, Marriam, Tiwari, Sandeep, Hassan, Syed S, Hanan, Fazal, Ramos, Rommel, Pereira, Ulisses, Barh, Debmalya, Figueiredo, Henrique César Pereira, Ussery, David W., Miyoshi, Anderson, Silva, Artur, Azevedo, Vasco
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325212/