Isocitrate dehydrogenase 1 mutations (IDH1) and p16/CDKN2A copy number change in conventional chondrosarcomas
To determine whether IDH1 mutations are present in primary and relapsed (local and distal) conventional central chondrosarcomas; and secondly, to assess if loss of p16/CDKN2A is associated with tumour grade progression, 102 tumour samples from 37 patients, including material from presenting and rela...
Main Authors: | Amary, M. Fernanda, Ye, Hongtao, Forbes, Georgina, Damato, Stephen, Maggiani, Francesca, Pollock, Robin, Tirabosco, Roberto, Flanagan, Adrienne M. |
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Format: | Online |
Language: | English |
Published: |
Springer Berlin Heidelberg
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325180/ |
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