Isocitrate dehydrogenase mutations: new opportunities for translational research
Over the last decade, comprehensive genome-wide sequencing studies have enabled us to find out unexpected genetic alterations of metabolism in cancer. An example is the identification of arginine missense mutations of isocitrate dehydrogenases-1 and -2 (IDH1/2) in glioma, acute myeloid leukemia (AML...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Korean Society for Biochemistry and Molecular Biology
2015
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578565/ |