BPIFB3 Regulates Autophagy and Coxsackievirus B Replication through a Noncanonical Pathway Independent of the Core Initiation Machinery
Enteroviruses require autophagy to facilitate the formation of autophagosome (AP)-like double-membrane vesicles that provide the scaffolding for RNA replication. Here, we identify bactericidal/permeability-increasing protein (BPI) fold-containing family B, member 3 (BPIFB3) as a gene whose silencing...
Main Authors: | Delorme-Axford, Elizabeth, Morosky, Stefanie, Bomberger, Jennifer, Stolz, Donna B., Jackson, William T., Coyne, Carolyn B. |
---|---|
Format: | Online |
Language: | English |
Published: |
American Society of Microbiology
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324245/ |
Similar Items
-
The Coxsackievirus B 3Cpro Protease Cleaves MAVS and TRIF to Attenuate Host Type I Interferon and Apoptotic Signaling
by: Mukherjee, Amitava, et al.
Published: (2011) -
At the crossroads of autophagy and infection: Noncanonical roles for ATG proteins in viral replication
by: Solvik, Tina, et al.
Published: (2016) -
Calcium signals and calpain-dependent necrosis are essential for release of coxsackievirus B from polarized intestinal epithelial cells
by: Bozym, Rebecca A., et al.
Published: (2011) -
The Actin Cytoskeleton as a Barrier to Virus Infection of Polarized Epithelial Cells
by: Delorme-Axford, Elizabeth, et al.
Published: (2011) -
LINEs of evidence: noncanonical DNA replication as an epigenetic determinant
by: Belan, Ekaterina
Published: (2013)