Pichia pastoris secretes recombinant proteins less efficiently than Chinese hamster ovary cells but allows higher space-time yields for less complex proteins

Pichia pastoris secretes recombinant proteins less efficiently than Chinese hamster ovary cells but allows higher space-time yields for less complex proteins

Chinese hamster ovary (CHO) cells are currently the workhorse of the biopharmaceutical industry. However, yeasts such as Pichia pastoris are about to enter this field. To compare their capability for recombinant protein secretion, P. pastoris strains and CHO cell lines producing human serum albumin...

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Bibliographic Details
Main Authors: Maccani, Andreas, Landes, Nils, Stadlmayr, Gerhard, Maresch, Daniel, Leitner, Christian, Maurer, Michael, Gasser, Brigitte, Ernst, Wolfgang, Kunert, Renate, Mattanovich, Diethard
Format: Online
Language:English
Published: WILEY-VCH Verlag 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315903/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315903/

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