In Pichia pastoris, growth rate regulates protein synthesis and secretion, mating and stress response
Protein production in yeasts is related to the specific growth rate μ. To elucidate on this correlation, we studied the transcriptome of Pichia pastoris at different specific growth rates by cultivating a strain secreting human serum albumin at μ = 0.015 to 0.15 h–1 in glucose-limited chemostats. Ge...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
WILEY-VCH Verlag
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162992/ |