Genetic Analysis of the Pathogenic Molecular Sub-phenotype Interferon Alpha Identifies Multiple Novel Loci Involved in Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disorder characterized by inflammation of multiple organ systems and dysregulated interferon responses. SLE is both genetically and phenotypically heterogeneous, greatly reducing the power of case-control studies in SLE. Elevated circulating...

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Bibliographic Details
Main Authors: Kariuki, Silvia N., Ghodke-Puranik, Yogita, Dorschner, Jessica M., Chrabot, Beverly S., Kelly, Jennifer A., Tsao, Betty P., Kimberly, Robert P., Alarcón-Riquelme, Marta E., Jacob, Chaim O., Criswell, Lindsey A., Sivils, Kathy L., Langefeld, Carl D., Harley, John B., Skol, Andrew D., Niewold, Timothy B.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305028/