Disparate roles of zinc in chemical hypoxia-induced neuronal death
Accumulating evidence has provided a causative role of zinc (Zn2+) in neuronal death following ischemic brain injury. Using a hypoxia model of primary cultured cortical neurons with hypoxia-inducing chemicals, cobalt chloride (1 mM CoCl2), deferoxamine (3 mM DFX), and sodium azide (2 mM NaN3), we ev...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304355/ |