Disparate roles of zinc in chemical hypoxia-induced neuronal death

Accumulating evidence has provided a causative role of zinc (Zn2+) in neuronal death following ischemic brain injury. Using a hypoxia model of primary cultured cortical neurons with hypoxia-inducing chemicals, cobalt chloride (1 mM CoCl2), deferoxamine (3 mM DFX), and sodium azide (2 mM NaN3), we ev...

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Bibliographic Details
Main Authors: Kim, Sujeong, Seo, Jung-Woo, Oh, Shin Bi, Kim, So Hee, Kim, Inki, Suh, Nayoung, Lee, Joo-Yong
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304355/